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Levamisole Hydrochloride killed our fish | 23 comments (23 topical, 0 editorial, 0 hidden)
Re: Levamisole Hydrochloride killed our fish (none / 0) (#15)
by inkmaker on Wed Apr 25, 2007 at 08:21:14 PM PST

<H2>The loss of the small fishes is regreatable but I must suggest the situation is not all that uncommon. Getting the dead parasite out of the infested fish is a big problem for the fish. I plan to post pictures from treatments this weekend.
<BR>
A recent email follows:</H2>
~~~~~~~~~~~~~~~~

Well then, Great news!

The major thing at this point is to get the dead worms out of the fish. They actually freeze and are paralyzed by the drug. This kills them. Once dead or at least affected by the drug they may just fall out - we hope. If that is so then there should be little problem. They don't usually shrink in size, most likely they have fallen out of the fishes.

It is time to watch the fishes and keep them well fed and active. It is good to watch the group and be ready to change water.

Good luck and keep me informed please. I would appreciate any pictures.

Charles Harrison

Hello Charles,

Thanks for your reply.  I was able to find Levamisole HCI at my local feed store, since I live in a big ranching county in Texas.  On one hand, I wish I had waited to order from you, because your prices are much cheaper than I found in town.  On the other hand, it's worth it to have begun treatment as quickly as possible, I'm not sure she would have held out until the shipment arrived.

I have begun treatment following the directions I found on your web site.  Your instructions here clear up a few points for me, thanks!  Tonight will be 48 hours into treatment.  The infested angel and the other fish in the tank are doing well.  I no longer see the worms protruding from her vent.  I understand that they may have simply withdrawn inside, so the war may not be won.  I will continue treatment per your instructions.

I have been so far unable to get a good shot of the worms.  As you know, they are tiny, and she is fast!  Also, she is in a hex shaped tank, for some reason, that glass distorts my shots.  If I do get a good shot, I will be delighted to send it on to you for use on your web page.

Thanks so much,
Dawn

----- Original Message -----
From: <mailto:charles@inkmkr.com>Charles Harrison
To: Dawn
Sent: Saturday, July 09, 2005 10:31 PM
Subject: Re: camellanus coti emergency!

Dear Charles,

Hello, my name is Dawn and I was sent to you by the fine folks at Badman's Tropical Fish.

 Hello Dawn,

Sorry about the time it has taken me to get back to you.  I am just now getting back to my e-mail.   Regarding your  adult angelfish,  if there are female camellanus worms  protruding - that would indicate that the gut is probably full of the nematodes. That presents quite a problem for the fish once these nematodes are dead.  The fish will have to digest the remains of the dead nematode  or expelled them and that is very difficult for the large intestines to do since it is their primary responsibility to remove water from the feces.  We lose many more fishes to the dead parasite than any other problem.

The nematode may be spread from  tank to tank in many different ways.  It is unfortunate that this parasite is so virulent.  There  doesn't seem to be any treatment available at  the local fish stores.  As a matter of fact most of the local fish store personnel  really has no idea of the problems caused by this parasite.

The treatment for the nematodes is Levamisole HCl,  It is a water soluble compound.  5 grams  treats 100 gal. of water.  You'll want to have enough Levamisole to treat the water twice.  If you have to treat it total of  265 gal. and will probably want to treat it twice, you'll need about 30 gm.  That's gonna cost you $30.00 plus postage.  I don't want you have to chase the nematode around for several months.  The idea is to get control of the environment and manage the problem so you don't have to go back to treat the ailing fish again.

Once you treat the water with the drug and are able to kill off  the parasite, you will need to change the water, all of it.  If you haven't done a 100% water change, now is a good time to get that started.  Many aquarist change only a small portion of the water at a time. If you kill off all lot of parasites, snails, etc. you're going to have quite a bacteria over growth  and the only way to get rid of that is to change all of the water.  So get the fish used to major water changes.

 Another important issue is to keep the fish as healthy as possible.  Live food that the fish enjoy eating will help to push the dead worms through the gut. The medication  actually paralyzes the worms and this causes them to die.  if they remain hooked inside the fish's gut they're going to have to be pushed out & among the best ways to do it as to feed the fish lots of live food.

 OK, what you need to do -  give me your address to send the medication to  and I will  get 30 g  ready to ship to you on Monday.  Since one of your adult Angels  has already died it is quite likely you will not be able to save the  female.  they're just too many animals in the gut that you are going to kill and I don't think she can pass all of them.

 There is one item I would really appreciate from you,  I noticed that you're quite a photographer.  Is there any possible way you could get some pictures of your angelfishes vent and the protruding nematodes?  I have several photographs of many different fishes  but I don't have  any angelfish.

 let me hear back from you.

 Charles H.

I am emailing about my breeding pair of Angels.  I went away on vacation for a week, when I came home the male angel was dead.  Now, looking at the female closely, I see about 8 red things sticking out from her anus.  With help from the folks at Badmans it has been diagnosed at camellanus coti.  I have been told that you can and will give me advice, and that I can buy the medicine from you to try to cure my fish.  I have also been told that I need to treat all of my tanks since this worm can spread by using the same nets and the same python in all my tanks.  I have 10 tanks totalling 265 gallons of water.  One of my 10 gallon tanks has only snails, no fish, do I need to treat them as well?

Please advise me of how much medicine I need, and what the price will be.  I see you accept paypal, so please include their fees in the price.  I'm guessing that I need this med as fast as possible, so please include the fees for the fastest shipping option.

Can she be saved with so many of the worms coming out of her?  Any advice and hand-holding you can give me will be vastly appreciated!

http://www.InkForYourPrinter.com



Re: Levamisole Hydrochloride killed our fish (none / 0) (#19)
by Scott Lockwood on Thu Apr 26, 2007 at 08:19:33 PM PST

Can you look at This and tell me if my math is wrong?

"I love to visit PetSmart's Tropical Fish Dept. to see what new diseases are around today." -- inkmaker
[ Parent ]



That was a confusing discussion. I wasn't sure (none / 0) (#20)
by unclescott on Fri Apr 27, 2007 at 04:45:30 PM PST

where you got your 695 milligrams. The various formulas for mixing up assorted stock solutions lost me too.

I think our confusion was partly in converting ounces into grams into milligrams. Looking back it shouldn’t have been so hard. We muddied the water by adding a set amount of the Levamisole to different quantities of water.

Eventually a couple of us started with Charles's suggested 5 grams for 100 gallons. That easily breaks down into 1 gram for 20 gallons, 1/2 a gram for 10 gallons. Charles himself had previously suggested saving some of the Levamisole by just filling the 10-gallon tank half way and halving that half gram.

You had, I believe 52g, of which 46.8g was pure Levamisole. That is not a whole lot of extra filler.

When miskairal pointed out that a standard teaspoon held 5g, I though, why didn’t I just suggest that you take 10 baggies, put a level teaspoon’s worth in each and maybe one of those jells which pulls moisture from the air in each baggie as well. Then you could use 1/5 or 1/10 of a baggie for your treatment. And what guy has ever measured a LEVEL tablespoon? ;)

Yesterday I needed to mix a certain(eyeballed) amount of sodium thiosulfate to renew my 30-gallon RubberMaid trash is used to declorinate previously bleached equipment. It takes swishing it around in a jar with a little hot water to dissolve most of it. Then I added enough cold water that I could pour that pint into the larger container and it was good to go.I don't know why we got so hung up on those various solutions. Maybe different people  had different quarantine containers around the house.

Oh! And I'll remember that 1 ounce = 28.35 grams or 28,349.5231249 milligrams. That's just the thing to bring up at breakfast. ;)

[ Parent ]



Hey now! (none / 0) (#21)
by Scott Lockwood on Sat Apr 28, 2007 at 08:33:33 AM PST

And what guy has ever measured a LEVEL tablespoon? ;)

Uh, THIS guy, for one! :-)

Remember, I was a lab tech, so being anal retentive goes with the job. That's why this is so distressing to me - I don't want my math error to be responsible for someone else's dead fish! Now mind you, I'm skeptical that it is, but I have taken the precaution of bumping that article back up to the front page, and have put a big warning on it.

Sigh. I wish Charles would weigh in (ba-dump bump) on the issue.

"I love to visit PetSmart's Tropical Fish Dept. to see what new diseases are around today." -- inkmaker
[ Parent ]



Levamisole Hydrochloride killed our fish | 23 comments (23 topical, 0 editorial, 0 hidden)
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